Sylvia A. Lopez-Vetrone

Breadcrumb

Sylvia VetroneJames Irvine Foundation Chair in Biological Sciences
Associate Professor
Department of Biology

Science & Learning Center 305
562.907.4200 x4424
svetrone@whittier.edu

Mailing address
Whittier College, Department of Biology
13406 Philadelphia St., Whittier, CA 90608

Academic History

B.A. Biology, Minor in Chemistry
Whittier College, 1999

Ph.D. Molecular, Cellular, and Integrative Physiology
University of California, Los Angeles, 2008

Academic Focus

  • Cell Biology
  • Cellular and molecular basis of disease

Research Focus

Immunology, oncology, disease pathology, oxidative stress, aging, neuromuscular disorders, effect of plant nutraceuticals on health and cancer, and biosensor development & validation for pathogenic detection.

Professional Memberships

  • American Society for Cell Biology, 2014
  • Genetics Society of America, 2013
  • National Academies Education Fellow in the Life Sciences, 2012
  • Institute of Biological Engineering (IBE) Faculty Member, 2012
  • Society for the Advancement of Chicanos and Native Americans in Science (SACNAS) Faculty Member, 2011
  • HACU Faculty Caucus, 2009
  • HACU, Health Science Advisory Committee Member, 2009

Selected Publications

  • Ghosh,S., Vetrone, S.A., Strenberg, P.W. Non-neuronal cell outgrowth in C. elegans. Worm, 2017, 6:3-4
  • Capote, J., Kramerova, I., Martinez, L., Vetrone, S.A., Barton, E.R., Sweeney, H.L., Miceli, M.C., and Spencer, M.J. Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a proregenerative phenotype. J. Cell Biology, 2016
  • Ermolova, N.M., Martinez, L., Vetrone, S.A., Jordan, M.C., Roos, K.P., Sweeny, H.L., and Spencer, M.J. Long term administration of the TNF blocking drug Remicade (cV1q) to mdx mice reduces skeletal and cardiac muscle fibrosis, but negatively impacts cardiac function. Neuromuscular Disorders 2014
  • Callaway MK, Ochoa JM, Perez EE, Ulrich PE, Alocilja, E.C., and Vetrone, S.A. Investigation of the Toxicity of Amine-coated, Carboxyl-coated and Ployaniline-coated Feo Magnetic Nanoparticles in Caenorhabditis elegans. JBiosens Bioelectron, 2013, 4: 145.
  • Vetrone, S.A., Huarng, M., Alocilja, E.C., Detection of Non-PCR Amplified S. enteritidis Genomic DNA from Food Matrices Using a Gold-Nanoparticle DNA Biosensor: A Proof-of-Concept Study, Sensors, 2012, 12, 10487-10499
  • Vetrone, S.A., Montecino-Rodriguez, E., Kramerova, I., Kudryashova, E., Granchelli, J. Hoffman, E.P., Liu, S., Miceli, C., and Spencer, M.J., Osteopontin Promotes Fibrosis in MDX Dystrophy. Journal of Clinical Investigations, 2009 Jun; 119(6): 1583-94.

Current Research Projects

Professor Sylvia Vetrone is an immunologist whose current research focuses on investigating the potential health and anti-cancer benefits of cultural and popular nutraceuticals (plant derived chemicals and extracts), validating nanoparticle DNA-based biosensors for the detection of microbial pathogens, and assessing the potential environmental and health effects of nanoparticles. Using both in vitro and in vivo models, Professor Vetrone and her students explore the health, immunological, and anti-proliferative effects of effects of nutraceuticals or synthetic nanoparticles on longevity, reproduction, metabolism, and immune function of human cancer cell lines and the nematode model, Caenorhabditis elegans. Through this research work, Professor Vetrone and her students aim to better understand the mechanisms through which natural supplements impact the cellular integrity of organisms, and how they may be harnessed for therapeutic purposes. Additionally, her research team validates nanoparticle DNA-based biosensors for the use in detection of bacterial pathogens in liquid and solid foodstuffs, that pose potential health and bioterrorism threats.